Issue compiled and edited by Kevin Fox and Michael Stryker
Hebbian plasticity is widely considered to be the mechanism by which information can be coded and retained in neurones in the brain. Homeostatic plasticity moves the neurone back toward its original state following a perturbation, including perturbations produced by Hebbian plasticity. How then does homeostatic plasticity avoid erasing the Hebbian coded information? To understand how plasticity works in the brain, and therefore to understand learning, memory, sensory adaptation, development and recovery from injury, requires development of a theory of plasticity that integrates both forms of plasticity into a whole.
This theme issue contains reviews, viewpoints, position papers and original research articles all aimed at tackling the question of how Hebbian and Homeostatic plasticity can be integrated and their opposite effects reconciled in a single theory that explains plasticity, learning and memory.
This issue arises from a Royal Society discussion meeting held in April 2016. More information, and audio recordings of the talks, can be found here.
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