The basic steps of protein synthesis are carried out by the ribosome, a very large and complex ribonucleoprotein particle. In keeping with its proposed emergence from an RNA world, all three of its core mechanisms—aminoacyl-tRNA selection, catalysis of peptide bond formation and coupled translocation of mRNA and tRNA—are embodied in the properties of ribosomal RNA, while its proteins play a supportive role.
This article is part of the themed issue ‘Perspectives on the ribosome’.
One contribution of 11 to a theme issue ‘Perspectives on the ribosome’.
- Accepted November 16, 2016.
- © 2017 The Author(s)
Published by the Royal Society. All rights reserved.