What is the function of the claustrum?

Francis C Crick, Christof Koch

Abstract

The claustrum is a thin, irregular, sheet-like neuronal structure hidden beneath the inner surface of the neocortex in the general region of the insula. Its function is enigmatic. Its anatomy is quite remarkable in that it receives input from almost all regions of cortex and projects back to almost all regions of cortex. We here briefly summarize what is known about the claustrum, speculate on its possible relationship to the processes that give rise to integrated conscious percepts, propose mechanisms that enable information to travel widely within the claustrum and discuss experiments to address these questions.

Footnotes

  • Deceased 28 July 2004

  • Received January 18, 2005.
  • Accepted March 29, 2005.
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